Disease: Amyotrophic Lateral Sclerosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC5 P13010 X-ray repair cross complementing 5 Enzyme 1.00 0.554 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TICAM1 Q8IUC6 toll like receptor adaptor molecule 1 0.593 0.846
TACR1 P25103 tachykinin receptor 1 G-protein coupled receptor 3.8E-04 0.502 0.885
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885